Nineteen years ago, Barbara Bigelow was diagnosed with breast cancer shortly after her two older sisters were diagnosed with the same type of cancer. After she finished a treatment regimen of surgery, chemotherapy, and radiation, her older sister passed away from metastatic breast cancer. Barbara then decided to have major preventive surgeries to further reduce her risk of recurrence. In 2015, she learned that her cancer had metastasized. After several failed treatments, Barbara enrolled in a cancer immunotherapy clinical trial in January 2016. Despite initially experiencing debilitating side effects, she has been cancer- and treatment-free for five years. Though Barbara continues to experience long-term side effects, she is grateful to be alive, passionate about advocacy work (including as a CRI ImmunoAdvocate), and enjoying life with her husband, daughters, and new grandson.